Physicians

Prism™ treatment plans based on fMRI and DTI studies deliver treatment that is faster, safer and more effective for the patient. Pre-treatment mapping identifies functional structures to avoid during treatment. Prism mapping speeds cortical localization using conventional electrode stimulation in the operating room. Avoiding functional structures during treatment dramatically reduces the risk and incidence of treatment-related deficits.

Prism’s breakthrough imaging technology increases clinical productivity. Post processing that used to take hours is now done in minutes by trained technologists. Clinical interpretation is fast and accurate. Critical spatial relationships are established across multiple image volumes in a single view. The physician interface includes a powerful set of tools that are useful in validating data quality, highlighting regions of interest and identifying overlapping activation patterns.

Resources

• Ulmer, The role of diffusion tensor imaging.
  The role of diffusion tensor imaging in establishing the proximity of tumor borders to functional brain systems: implications for preoperative risk assessments and postoperative outcomes.
  Technol Cancer Res Treat. 2004 Dec;3(6):567-76.
  PMID: 15560714 [PubMed - indexed for MEDLINE]
• Schmainda, Characterization of a first-pass gradient-echo spin-echo method.
  Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis.
  AJNR Am J Neuroradiol. 2004 Oct;25(9):1524-32. Erratum in: AJNR Am J Neuroradiol. 2005 Mar;26(3):686. Baddrudoja, Michael A [corrected to Badruddoja, Michael A].
  PMID: 15502131 [PubMed - indexed for MEDLINE]
• DeYoe, Functional magnetic resonance imaging of the human brain.
  Functional magnetic resonance imaging (FMRI) of the human brain.
  J Neurosci Methods. 1994 Oct;54(2):171-87. Review.
  PMID: 7869750 [PubMed - indexed for MEDLINE]
• Holodny, Clinical Applications of fMRI and DTI.
  Clinical Applications of fMRI and DTI. ISMRM 2006.
• Petrella, Preoperative Functional MR Imaging Localization of Language and Motor Areas.
  Preoperative Functional MR Imaging Localization of Language and Motor Areas: Effect on Therapeutic Decision Making in Patients with Potentially Resectable Brain Tumors. Radiology 2006 240(3):793-802.