Medical Advisory Board

Meng Law, MD
Professor of Radiology and Neurological Surgery, Director of Neuroradiology at the University of Southern California

Law M, Young RJ, Babb JS, Peccerelli N, Chheang S, Gruber ML, Miller DC, Golfinos JG, Zagzag D, Johnson G.
Gliomas: Predicting Time to Progression or Survival with Cerebral Blood Volume Measurements at Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging.
Radiology. 2008 Mar 18; [Epub ahead of print]

Lui YW, Law M, Chacko-Mathew J, Babb JS, Tuvia K, Allen JC, Zagzag D, Johnson G.
Brainstem corticospinal tract diffusion tensor imaging in patients with primary posterior fossa neoplasms stratified by tumor type: a study of association with motor weakness and outcome.
Neurosurgery. 2007 Dec;61(6):1199-207; discussion 1207-8.

Young R, Babb J, Law M, Pollack E, Johnson G.
Comparison of region-of-interest analysis with three different histogram analysis methods in the determination of perfusion metrics in patients with brain gliomas.
J Magn Reson Imaging. 2007 Oct;26(4):1053-63.

Pollack E, Bhaya A, Law M.
Differentiating intracranial aspergillosis from a high grade glioma using MRI and MR spectroscopic imaging.
J Neuroimaging. 2007 Oct;17(4):361-6.

Lu H, Law M, Ge Y, Hesseltine SM, Rapalino O, Jensen JH, Helpern JA.
Quantitative measurement of spinal cord blood volume in humans using vascular-space-occupancy MRI.
NMR Biomed. 2008 Apr;21(3):226-32.

Law M, Brodsky JE, Babb J, Rosenblum M, Miller DC, Zagzag D, Gruber ML, Johnson G.
High cerebral blood volume in human gliomas predicts deletion of chromosome 1p: Preliminary results of molecular studies in gliomas with elevated perfusion.
J Magn Reson Imaging. 2007 Jun;25(6):1113-9.

Kim MJ, Provenzale JM, Law M.
Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases.
Top Magn Reson Imaging. 2006 Aug;17(4):265-74. Review.

Pivawer G, Law M, Zagzag D.
Perfusion MR imaging and proton MR spectroscopic imaging in differentiating necrotizing cerebritis from glioblastoma multiforme.
Magn Reson Imaging. 2007 Feb;25(2):238-43. Epub 2006 Nov 20.

Cunningham PM, Law M, Schweitzer ME.
High-field MRI.
Orthop Clin North Am. 2006 Jul;37(3):321-9, vi. Review.

Orbach DB, Wu C, Law M, Babb JS, Lee R, Padua A, Knopp EA.
Comparing real-world advantages for the clinical neuroradiologist between a high field (3 T), a phased array (1.5 T) vs. a single-channel 1.5-T MR system.
J Magn Reson Imaging. 2006 Jul;24(1):16-24.

Elijovich L, Kazmi K, Gauvrit JY, Law M.
The emerging role of multidetector row CT angiography in the diagnosis of cervical arterial dissection: preliminary study.
Neuroradiology. 2006 Sep;48(9):606-12. Epub 2006 Jun 3.

Law M, Oh S, Johnson G, Babb JS, Zagzag D, Golfinos J, Kelly PJ.
Perfusion magnetic resonance imaging predicts patient outcome as an adjunct to histopathology: a second reference standard in the surgical and nonsurgical treatment of low-grade gliomas.
Neurosurgery. 2006 Jun;58(6):1099-107; discussion 1099-107.

Lui YW, Law M, Jafar JJ, Douglas A, Nelson PK.
Perfusion and diffusion tensor imaging in a patient with locked-in syndrome after neurosurgical vascular bypass and endovascular embolization of a basilar artery aneurysm: case report.
Neurosurgery. 2006 Apr;58(4):E794; discussion E794.

Law M, Oh S, Babb JS, Wang E, Inglese M, Zagzag D, Knopp EA, Johnson G.
Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response.
Radiology. 2006 Feb;238(2):658-67. Epub 2006 Jan 5.

Ge Y, Law M, Grossman RI.
Applications of diffusion tensor MR imaging in multiple sclerosis.
Ann N Y Acad Sci. 2005 Dec;1064:202-19. Review.

Gagner JP, Law M, Fischer I, Newcomb EW, Zagzag D.
Angiogenesis in gliomas: imaging and experimental therapeutics.
Brain Pathol. 2005 Oct;15(4):342-63. Review.

Fischer I, Gagner JP, Law M, Newcomb EW, Zagzag D.
Angiogenesis in gliomas: biology and molecular pathophysiology.
Brain Pathol. 2005 Oct;15(4):297-310. Review.

Lu H, Law M, Johnson G, Ge Y, van Zijl PC, Helpern JA.
Novel approach to the measurement of absolute cerebral blood volume using vascular-space-occupancy magnetic resonance imaging.
Magn Reson Med. 2005 Dec;54(6):1403-11.

Ge Y, Law M, Herbert J, Grossman RI.
Prominent perivenular spaces in multiple sclerosis as a sign of perivascular inflammation in primary demyelination.
AJNR Am J Neuroradiol. 2005 Oct;26(9):2316-9.

Ge Y, Law M, Johnson G, Herbert J, Babb JS, Mannon LJ, Grossman RI.
Dynamic susceptibility contrast perfusion MR imaging of multiple sclerosis lesions: characterizing hemodynamic impairment and inflammatory activity.
AJNR Am J Neuroradiol. 2005 Jun-Jul;26(6):1539-47.

Law M.
MR spectroscopy of brain tumors.
Top Magn Reson Imaging. 2004 Oct;15(5):291-313. Review.

Law M, Hamburger M, Johnson G, Inglese M, Londono A, Golfinos J, Zagzag D, Knopp EA.
Differentiating surgical from non-surgical lesions using perfusion MR imaging and proton MR spectroscopic imaging.
Technol Cancer Res Treat. 2004 Dec;3(6):557-65. Review.

Ge Y, Law M, Johnson G, Herbert J, Babb JS, Mannon LJ, Grossman RI.
Preferential occult injury of corpus callosum in multiple sclerosis measured by diffusion tensor imaging.
J Magn Reson Imaging. 2004 Jul;20(1):1-7.

Lu S, Ahn D, Johnson G, Law M, Zagzag D, Grossman RI.
Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index.
Radiology. 2004 Jul;232(1):221-8.

Law M, Kazmi K, Wetzel S, Wang E, Iacob C, Zagzag D, Golfinos JG, Johnson G.
Dynamic susceptibility contrast-enhanced perfusion and conventional MR imaging findings for adult patients with cerebral primitive neuroectodermal tumors.
AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):997-1005.

Law M, Meltzer DE, Wetzel SG, Yang S, Knopp EA, Golfinos J, Johnson G.
Conventional MR imaging with simultaneous measurements of cerebral blood volume and vascular permeability in ganglioglioma.
Magn Reson Imaging. 2004 Jun;22(5):599-606.

Law M, Saindane AM, Ge Y, Babb JS, Johnson G, Mannon LJ, Herbert J, Grossman RI.
Microvascular abnormality in relapsing-remitting multiple sclerosis: perfusion MR imaging findings in normal-appearing white matter.
Radiology. 2004 Jun;231(3):645-52.

Law M, Yang S, Babb JS, Knopp EA, Golfinos JG, Zagzag D, Johnson G.
Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade.
AJNR Am J Neuroradiol. 2004 May;25(5):746-55.

Law M, Yang S, Wang H, Babb JS, Johnson G, Cha S, Knopp EA, Zagzag D.
Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging.
AJNR Am J Neuroradiol. 2003 Nov-Dec;24(10):1989-98.

Yang S, Law M, Zagzag D, Wu HH, Cha S, Golfinos JG, Knopp EA, Johnson G.
Dynamic contrast-enhanced perfusion MR imaging measurements of endothelial permeability: differentiation between atypical and typical meningiomas.
AJNR Am J Neuroradiol. 2003 Sep;24(8):1554-9.

Law M, Teicher N, Zagzag D, Knopp EA.
Dynamic contrast enhanced perfusion MRI in mycosis fungoides.
J Magn Reson Imaging. 2003 Sep;18(3):364-7.

Wetzel SG, Law M, Lee VS, Cha S, Johnson G, Nelson K.
Imaging of the intracranial venous system with a contrast-enhanced volumetric interpolated examination.
Eur Radiol. 2003 May;13(5):1010-8. Epub 2002 Nov 8.

Kothary N, Law M, Cha S, Zagzag D.
Conventional and perfusion MR imaging of parafalcine chondrosarcoma.
AJNR Am J Neuroradiol. 2003 Feb;24(2):245-8.

Wetzel SG, Cha S, Law M, Johnson G, Golfinos J, Lee P, Nelson PK.
Preoperative assessment of intracranial tumors with perfusion MR and a volumetric interpolated examination: a comparative study with DSA.
AJNR Am J Neuroradiol. 2002 Nov-Dec;23(10):1767-74.

Saindane AM, Cha S, Law M, Xue X, Knopp EA, Zagzag D.
Proton MR spectroscopy of tumefactive demyelinating lesions.
AJNR Am J Neuroradiol. 2002 Sep;23(8):1378-86.

Wetzel SG, Cha S, Johnson G, Lee P, Law M, Kasow DL, Pierce SD, Xue X.
Relative cerebral blood volume measurements in intracranial mass lesions: interobserver and intraobserver reproducibility study.
Radiology. 2002 Sep;224(3):797-803.

Law M, Cha S, Knopp EA, Johnson G, Arnett J, Litt AW.
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.
Radiology. 2002 Mar;222(3):715-21.